for example...
nick fury in schleuper (that area in hell were you fight a bunch of demonic souls), cause his smg tears through them like a knife through butter.
daken in madarin's palace because he can go stealth and take down all the clay soldiers in a single melee. and use his powa's on the clay wariors. it's really quite great.
schleuper, that one killed me. though the original nameis funny too: sepulcher. I prefer blade's gun move above that, as thegun shoots through walls.
don't go dissin the smg. it may suck against most enemies, but i took down mephisto mainly by strafing around him in circles with that gun.
then I say Forge's stun smg. It sure as hell beats Fury's!